It worked again!

This was more of an annoyance than anything, but over Friday and Saturday, I started to get a head cold. No sore throat or aches but a stuffy nose and head, general fatigue. Once again, I started up with my favorite combo of beta glucan, Resist Immune and extra vitamin C. I normally take about 4-5 grams a day, so this time I was only adding a few extra grams. Today, Sunday, the head cold is virtually gone, energy is better. This happens consistently when I’ve used this combo and a few people I’ve tried this with have had similar success. I’d say it is worth a shot! Others also swear by Heath Concerns Cold Away (we are out just at the moment but should have more in in a couple of weeks.) What works for you?

Taking Vitamin D3 supplements for more than 3 years linked to lower mortality

We’ve heard a lot about Vitamin D in the past few years. There have been studies linking low Vitamin D levels to a host of health issues, from heightened risk of cardiovascular disease, to higher probability of developing the flu, especially during the winter season, when you get less exposure to the sunshine that allows the body to produce its own supply of the vitamin.

Now here’s an interesting meta-analysis (=review of previously published research) that looks at the connection between long-term use of Vitamin D3 supplements (“long-term” defined, in this case, as more than three years). Reviewing data from 42 earlier trials, this investigation found that those who supplemented with Vitamin D for longer than three years had a significant reduction in mortality. Specifically, this research found that the following groups showed a lower risk of death when supplementing with Vitamin D over a period longer than three years: women, people under the age of 80, those taking a daily dose of 800IU or less of Vitamin D, and those participants with vitamin D insufficiency (defined as a baseline 25-hydroxyvitamin D level less than 50 nmol/L).

Here’s the conclusion reached by the researchers:

The data suggest that supplementation of vitamin D is effective in preventing overall mortality in a long-term treatment, whereas it is not significantly effective in a treatment duration shorter than 3 years. Future studies are needed to identify the efficacy of vitamin D on specific mortality, such as cancer and cardiovascular disease mortality in a long-term treatment duration.

Our comment: We’re not surprised that supplementing over a period of years proves, in this review, to be more beneficial than briefer periods of supplementing. Vitamin D, like many supplements, shouldn’t be seen as treatment for an acute condition. It doesn’t act like an antibiotic, which may clear up an infection with a couple weeks of treatment. Instead, think of the body as having a long-term, continual need for Vitamin D; and note as well that seasonal change, or a particular health status (for example, being HIV+), may lead to deficiency and thus increase your need for supplementing. We were somewhat surprised to see that a significantly lowered risk of mortality was found even with a moderate rate of supplementation (800 IU daily dose). On this Blog you can read about other research that links decreased risk of flu, for example, with a daily Vitamin D dose of 2000IU. At any rate, there are no known “adverse events” at either of these doses of the vitamin, so not to worry, whether you’re following the lower or a higher recommendation.

See the NYBC catalog for Vitamin D3 offerings:

http://nybcsecure.org/index.php?cPath=25

Reference:
Zheng Y, et al. Meta-analysis of long-term vitamin D supplementation on overall mortality. PLoS One. 2013 Dec 3;8(12):e82109. doi: 10.1371/journal.pone.0082109.

Who’s Afraid of Cold and Flu Season? Not NYBC!

As the days get shorter and we approach the end of October, here in the Northern Hemisphere many worry about the Cold and Flu Season. Colds and flus aren’t fun for anyone, and people with compromised immune systems may be especially vulnerable. Here are some recommendations from NYBC, both in the prevention department and in the symptom alleviation department. Using these supplements, we believe, can make the Cold and Flu Season a lot less scary!

Vitamin D. According to some recent thinking, the “cold and flu season” may actually be the “Vitamin D deficiency season.” As the days grow shorter, people get less sunshine, leading to a decline in the body’s levels of this vitamin, which is essential to good health in many more ways than we used to think. Taking Vitamin D during the winter may therefore be one of the most effective ways to prevent colds and flu. Many researchers who’ve studied Vitamin D now recommend at least 2000 IU/day, but those with a known deficiency may be advised to supplement at even higher levels. There’s a simple test available to check for Vitamin D deficiency – ask your doctor.

Cold Away. This blend of Chinese herbs from Health Concerns is designed to “clear external heat and alleviate symptoms of the common cold.” A key component of this formula is the herb andrographis, which in several recent US studies was found to significantly decrease cold symptoms and the duration of a cold; it may also be useful for prevention. (NYBC stocks over 20 varieties of Traditional Chinese Medicine formulas, by the way.)

Vitamin C. Many good studies have shown a decrease in cold symptom duration, but no benefit for prevention. According to a guide to natural products published by the American Pharmacists’ Association in 2006, taking between one and three grams of Vitamin C per day may decrease cold symptoms (sore throat, fatigue, runny nose) by one to 1½ days.*

N-acetylcysteine (NAC) supports respiratory and immune system function. It has been studied extensively for chronic bronchitis. NAC is also the antidote for acetaminophen poisoning, now the leading cause of liver disease in the US. (Acetaminophen’s best-known tradename is Tylenol®, but it’s also found in many other drugs, so it’s become all too easy to overdose–especially when you’re fighting cold or flu symptoms.)

One popular way to take NAC is to use PharmaNAC, notable for its careful quality control, pleasant “wildberry” flavor, and effervescent fizz!

Botanicals. In Traditional Chinese Medicine, astragalus is used for chronic respiratory infections, for colds and flu (both prevention and treatment) and for stress and fatigue. It contains complex sugar molecules called polysaccharides, which some studies show stimulate virus-fighting cells in the immune system. Researchers at the University of Texas and M.D. Anderson Cancer Center have turned up evidence that astragalus boosts immune responses in lab animals, and in human cells in lab dishes.

Probiotics. They say the best defense is a good offense, so consider upping your intake of the beneficial bacteria found naturally in such things as kefir (the lightly fermented milk beverage) and yogurt: they boost the flora in your intestinal tract, which is where an estimated 80% your immune system resides. Also note that NYBC stocks several varieties of probiotic supplements, including Jarrow’s Ultra Jarro-Dophilus, which has helped many maintain healthy digestive function, always a key to getting proper nutrition into your system and thus supporting immune strength.

And this just in: See posts on this blog for Beta Glucan, which, according to very recent research reports, may be of substantial benefit for fighting colds.

*Natural Products: A Case-Based Approach for Health Care Professionals, ed. Karen Shapiro. Washington, DC: American Pharmacists’ Assoc. (2006), “Cold and Flu,” pp. 173-192.

Beta Glucans to thwart colds?

Purely anecdotally, I’ve been using beta glucan to nip colds in the bud for years. If I can catch it, just at the onset of that first tickle, one or two do the trick. But if I forget or miss it and something’s trying to settle in, I wind up taking several through the day, along with increasing my dose of vitamin C from the usual 4 grams/day to about 6-8 grams (staying home especially if I’m worried about reaching bowel tolerance).

Some research is beginning to support these anecdotes of mine and several NYBC members. One small (industry) study showed reduced number of symptoms. Another study among 182 marathoners who may be more prone to colds due to suppressed mucosal immunity after a run, showed those using the beta glucans experienced “a 37% reduction in the number of cold/flu symptom days postmarathon compared to placebo (p = .026).” In a second study by the same researchers, they observed that beta glucan use was associated with “a 32% increase in salivary IgA (p = .048) at 2 hr after exercise compared to placebo.” That might provide a partial understanding of how these compounds work to stimulate a key feature of immunity.

Others have found that higher doses (8 g/day) may help lower LDL. Clearly, more studies can help us to understand the benefits, limitations and contraindications or side effects of this intriguing polysaccharides. Would that research were run based on science and the actual needs of medicine instead of the anti-science distortions of greed!

See nybuyersclub entry on Beta Glucan

Beta Glucan studied for colds: European Journal of Nutrition

NYBC has stocked Beta Glucan for quite a while, due to the variety of evidence about its capacity to enhance immune system function. On a more personal level, some at NYBC have taken to using it as a cold remedy or cold preventative, and generally–we’re speaking of the “anecdotal” level of evidence–have found it worthwhile.

Now we’re pleased to note a newly published, well-designed study in the European Journal of Nutrition that finds that beta glucan can reduce the number of colds by about 25%, and also acts to significantly decrease cold symptoms, including sleep disruption.

See NYBC’s product description:

http://nybcsecure.org/product_info.php?cPath=50&products_id=40

Reference: Auinger, A. et al. Yeast (1,3)-(1,6)-beta-glucan helps to maintain the body’s defence against pathogens: a double-blind, randomized, placebo-controlled, multicentric study in healthy subjects.
European Journal of Nutrition. January, 2013.

The Versatile Vitamin C

Most people associate Vitamin C with help in reducing cold symptoms. Indeed studies have shown that taking high-dose Vitamin C (500- 1000mg every hour) at the first sign of a cold can shorten its duration by one-third, helping to relieve symptoms faster. Vitamin C revs up the immune system by increasing the body’s production of antibodies, white blood cells, and interferon (a natural antiviral), and so it may be effective against many infections.

But that’s not the only way Vitamin C can keep you healthy. Here’s another major benefit of this versatile vitamin:

Joint health. Vitamin C’s anti-inflammatory properties help the body maintain cartilage, the all-important connective tissue that keeps your joints working smoothly. It’s also important to note that NSAIDS (nonsteroidal anti-inflammatory drugs), a whole group of drugs commonly used for arthritis pain, regularly deplete Vitamin C, so anyone taking these medications (which range from aspirin to prescription items like Celebrex) absolutely needs to replace the lost Vitamin C. In short, supplementing with 1000-3000mg of Vitamin C per day is essential if you’re also taking NSAIDS.

For some Vitamin C supplement choices, see NYBC’s descriptions of:

C1000- Ascorbic Acid Plus Olea

Vitamin C – Buffered

C-Esterol (Allergy Research Group)

What’s in Your Medicine Cabinet for Cold & Flu Season?

Here are some recommended supplements great for cold and flu season that have been the subject of recent, good research.

Vitamin D.  According to some recent thinking, the “cold and flu season” may actually be the “Vitamin D deficiency season.” As the days grow shorter, people get less sunshine, leading to a decline in the body’s levels of this vitamin, which is essential to good health in many more ways than we used to think. Taking Vitamin D during the winter may therefore be one of the most effective ways to prevent colds and flu. Many researchers who’ve studied Vitamin D now recommend at least 1000 IU/day, but those with a known deficiency may be advised to supplement at even higher levels. There’s a simple test available to check for Vitamin D deficiency – ask your doctor.

Cold Away. This blend of Chinese herbs from Health Concerns is designed to “clear external heat and alleviate symptoms of the common cold.” A key component of this formula is the herb andrographis, which in several recent US studies was found to significantly decrease cold symptoms and the duration of a cold; it may also be useful for prevention. (NYBC stocks  over 20 varieties of Traditional Chinese Medicine formulas, by the way.)

Vitamin C.  Many good studies have shown a decrease in cold symptom duration, but no benefit for prevention.  According to a guide to natural products published by the American Pharmacists’ Association in 2006, taking  between  one  and  three grams of Vitamin C per day may decrease cold symptoms (sore throat, fatigue, runny nose) by one to 1½ days.*

N-acetylcysteine (NAC) supports respiratory and immune system function. It has been studied extensively for chronic bronchitis. NAC is also the antidote for acetaminophen poisoning, now the leading cause of liver disease in the US. (Acetaminophen’s best-known tradename is Tylenol®, but it’s also found in many other drugs, so it’s become all too easy to overdose.)

One popular way to take NAC is to use PharmaNAC, notable for its careful quality control, pleasant “wildberry” flavor, and effervescent fizz!

Botanicals.  In Traditional Chinese Medicine, astragalus is used for chronic respiratory infections, for colds and flu (both prevention and treatment) and for stress and fatigue. It contains complex sugar molecules called polysaccharides, which some studies show stimulate virus-fighting cells in the immune system. Researchers at the University of Texas and M.D. Anderson Cancer Center have turned up convincing evidence that astragalus boosts immune responses in lab animals, and in human cells in lab dishes.

Elderberry extract (as found in Jarrow Formulas’ Wellness Optimizer) and American ginseng (found in two Health Concerns formulas) are two other botanicals that have been studied for cold and flu symptoms in recent North American research, with some promising results. Also, a study conducted by Israeli scientists showed that elderberry extract suppressed the growth of influenza viruses in lab dishes. The same research team reported that patients given the extract recovered from the flu faster. The perennially popular echinacea, however, has generally disappointed in cold prevention studies, but is still touted by some as beneficial at the onset of a cold.

Probiotics. They say the best defense is a good offense, so consider upping your intake of the beneficial bacteria found naturally in such things as kefir (the lightly fermented milk beverage) and yogurt: they boost the flora in your intestinal tract, which is where an estimated 80% your immune system resides.

NYBC stocks eight varieties of probiotic supplements, ranging from Florastor capsules, a favorite of international travelers, to the 40 billion beneficial baceteria-per-capsule Ultra Jarro-Dophilus, to Green Vibrance, a powder added to fruit juice or another beverage of choice (complimentary shaker cup included!).

*Natural Products: A Case-Based Approach for Health Care Professionals, ed. Karen Shapiro. Washington, DC: American Pharmacists’ Assoc. (2006), “Cold and Flu,” pp. 173-192.

Cold Away – with Andrographis

It’s the cold and flu season in the northern hemisphere, so we thought we’d remind everyone about the Health Concerns formula Cold Away, which includes the herb Andrographis. Recently the Mayo Clinic Guide to Alternative Medicine gave one of its “greenlights” of approval to Andrographis, which is a traditional Indian herb. As the Mayo experts say, Andrographis “has become popular as a remedy for upper respiratory infections, including cold and flu.” And, even more intriguing, “because of its immune-stimulating actions, the herb is also being studied as a possible treatment for many diseases, including cancer and HIV.”

Available at NYBC at
Cold Away.

Beta glucans and immune function

We were interested to see an entry by Dr. Mark Hyman a few days ago on the Huffington Post in which he spoke of beta glucans as part of an approach to staying healthy during cold and flu season: “Much research has shown that these compounds [beta-1,3-glucan and beta-1,6-glucans] up-regulate the function of our innate immune system. This part of your immune system is the first line of defense against viruses and bacteria. It helps your white blood cells bind to and kill viruses and bacteria.”

Here’s the description of the product Beta Max, which NYBC stocks from Jarrow. (The capsules are listed as containing 250 mg of at least 75% beta-1,3-glucan and beta-1,6-glucans.)

Beta glucans enhance the power of the immune system by activating a certain type of white blood cell known as macrophages. These cells patrol the body and fend off foreign invaders such as bacteria and fungi by engulfing them.

Research has shown that beta glucans also have a positive action on other white blood cells such as B-Lymphocytes, Natural Killer cells, and Suppressor T cells. The end outcome is that the body becomes better equipped at immune-mediated activities such as fighting off infection and combating cancer. Beta glucans have been used, therefore, in immune-compromised surgical patients to lower the rate of infection and both as a preventive measure against cancer and as an adjunct to chemotherapy.

Beta glucans are also well known to be effective in lowering blood lipid levels and is the key factor for why oat bran is so beneficial in this regard. Like other soluble fiber components, beta glucans work by binding cholesterol, facilitating its elimination from the body. Because beta glucans lower the bad LDL and increase the good HDL blood cholesterol levels, they are useful in preventing coronary heart disease.

Vitamin D3 and Flu Prevention

There has been rising interest in the past few years about Vitamin D’s potential for preventing/controlling flu and other respiratory illnesses.
One notable advocate for Vitamin D as a preventative against flu is Dr. John Cannell, lead author of a 2008 review article in the journal Virology. Cannell and his co-authors build on a decades-old insight from a British researcher, Hope-Simpson, who speculated that influenza was seasonal because of a co-factor related to sun exposure. The co-factor, this article asserts, is Vitamin D and its positive effects on immunity.

The second paragraph quoted below (from the same 2008 article in Virology) reports rather dramatic evidence that African-Americans, who are especially prone to Vitamin D deficiency, might very substantially decrease their susceptibility to colds and flu by supplementing with 2000IU daily during winter months.

Vitamin D, innate immunity, and influenza

Hope-Simpson’s model theorized that an unidentified “seasonal stimulus,” inextricably bound to solar radiation, substantially controlled the seasonality of influenza. Recent evidence suggests the “seasonal stimulus” may be seasonal impairments of the antimicrobial peptide (AMPs) systems crucial to innate immunity, impairments caused by dramatic seasonal fluctuations in 25-hydroxy-vitamin D [25(OH)D] levels. The evidence that vitamin D has profound effects on innate immunity is rapidly growing.

In fact, Aloia and Li-Ng presented evidence of a dramatic vitamin D preventative effect from a randomized controlled trial (RCT). In a post-hoc analysis of the side effect questions of their original three-year RCT, they discovered 104 post-menopausal African American women given vitamin D were three times less likely to report cold and flu symptoms than 104 placebo controls. A low dose (800 IU/day) not only reduced reported incidence, it abolished the seasonality of reported colds and flu. A higher dose (2000 IU/day), given during the last year of their trial, virtually eradicated all reports of colds or flu. Recent discoveries about vitamin D’s mechanism of action in combating infections led Science News to suggest that vitamin D is the “antibiotic vitamin” due primarily to its robust effects on innate immunity.

References:

Cannell, John J, Michael Zasloff, Cedric F Garland, Robert Scragg and Edward Giovannucci. On the epidemiology of influenza. Virology Journal 2008, 5:29. We accessed this 11/10/2009 at http://www.virologyj.com/content/5/1/29.

Aloia J F, Li-Ng M: Epidemic influenza and vitamin D. Epidemiol Infect 2007; 135: 1095–1096.

See the NYBC entry Vitamin D3 2500IU for additional information. This format of D3 is a convenient way to supplement at approximately the levels discussed by Cannell and others. (NYBC also stocks D3 1000IU and D3 400IU formats.)

What’s in Your Medicine Cabinet for Cold and Flu Season?

What’s in Your Medicine Cabinet for Cold and Flu Season?

As the cold and flu season approaches, don’t forget the supplements! Here are some good choices for preventing colds and flus, or for lessening symptoms:

Vitamin D. According to some recent thinking, the “cold and flu season” may actually be the “Vitamin D deficiency season.” As the days grow shorter, people get less sunshine, leading to a decline in the body’s levels of this vitamin, which is essential to good health in many more ways than we used to think. Supplementing with Vitamin D during the winter may therefore be one of the most effective ways to prevent colds and flu. Many researchers who’ve studied Vitamin D now recommend at least 1000 IU/day, but those with a known deficiency may be advised to supplement at even higher levels. Our #1 recommendation for cold and flu season! See NYBC’s D-3 2500IU or D3 1000IU or D3 400IU.

Cold Away. This Health Concerns blend of Chinese herbs is designed to “clear external heat and alleviate symptoms of the common cold.” A key component of this formula is the herb Andrographis, which has been studied in several US trials in the last decade, and was found to significantly decrease cold symptoms and the duration of a cold. See NYBC’s Cold Away.

Vitamin C. Many good studies have shown a decrease in cold symptom duration, but no benefit for prevention. According to a guide to natural products published by the American Pharmacists’ Association in 2006, taking between 1 and 3 grams of Vitamin C per day may decrease cold symptoms (sore throat, fatigue, runny nose) by 1 – 1 ½ days. See NYBC’s C1000 – Ascorbic Acid with Olea Fruit Extract, or C -Buffered Vitamin C (easier on the stomach), or Super C Powder.

NAC (PharmaNAC). N-acetylcysteine (NAC) supports respiratory and immune system function. It has been studied extensively for chronic bronchitis. NAC is also the antidote for acetaminophen poisoning, now the leading cause of liver disease in the USA. (Acetaminophen’s best-known tradename is Tylenol, but it’s also found in many other meds, and so it’s become all too easy to overdose. We like PharmaNAC for its quality packaging, wildberry flavor & fizz! See NYBC’s PharmaNAC.

Botanicals. In Traditional Chinese Medicine, Astragalus is used for chronic respiratory infections, for colds and flu (both prevention and treatment) and for stress and fatigue. (This herb is a favorite of integrative medicine specialist Dr. Andrew Weil.) An elderberry extract and American ginseng are two other botanicals that have been studied for cold and flu symptoms in recent North American research, with some promising results. The popular Echinacea, however, has generally disappointed in cold prevention studies.