In The News: CoQ10 Proves Its Worth Again

Heart To Heart: News & Tips For A Healthy Heart

New research on the supplement CoQ10, recently published in American and European medical journals, shows that it increases survival rates and decreases hospitalizations for people being treated for heart failure. CoQ10 (also called Coenzyme Q10, among other names) is a powerful antioxidant and acts as an essential factor in the heart’s energy production. In the past, clinical studies have provided evidence of its value as an adjunct treatment for angina, congestive heart failure, arrhythmia, and hypertension (high blood pressure). In addition, researchers have found that statin drugs deplete CoQ10, and so it has been suggested that people taking these cholesterol-lowering drugs should also use CoQ10 to support healthy heart function.

CoQ10 (also called Coenzyme Q10 and ubiquinone, among other names) is a powerful antioxidant and acts as an essential factor in the heart’s energy production. A naturally occurring and powerful antioxidant nutrient, it retards free radical formation in biological systems, and resembles vitamin E and vitamin K in chemical structure. Biochemically, it functions much like vitamin E in that it participates in antioxidant and free radical reactions. 

NOW AVAILABLE FROM NYBC’S ONLINE CO-OP:
Jarrow Formulas’ Q-Absorb, available in two strengths, utilizes a “completely natural proliposome lipid soluble delivery system clinically shown in humans to increase Co-Q10 levels up to 400% – three to four times better absorbed than chewable Co-Q10 tablets.” Price: $21- $29.

Douglas Labs’ Cardio Edge* employs plant sterols (phytosterols) from soy, Sytrinol (a proprietary extract of polymethoxylated flavones and tocotrienols from citrus and palm fruits), and pomegranate extract. Their Ultra Coenzyme Q10 ($121.60) has 60 chewable tablets with 200 mg CoQ10 combined with 500 mg lecithin.

* Note: Prices on Douglas Labs’ products are considerably lower for NYBC members!

The study lasted for two years and compared heart failure patients taking 100mg CoQ10 three times per day with patients who were not taking the supplement. By the end of the two-year period, the CoQ10 group showed a significantly lower rate of hospitalization for heart failure, significantly better functional capacity, and a significantly lower rate of death from cardiovascular disease.

NYBC has stocked CoQ10 since our founding, and has recently expanded its offerings. We’re happy that we’ve been able to provide this important supplement at discounted prices to our members over the years, and we’re happier still to see this new research strengthening the case for a supplement that already had a considerable amount of evidence demonstrating its benefit for heart health.

Here are some additional NYBC suggestions for cardiovascular health. All are based on our reading of the always-evolving research on nutrition and nutritional supplements:

Eating fatty fish (such as wild salmon) once or twice a week is an excellent approach to maintaining cardiovascular health; however, regular supplementation with fish oil can also provide the omega-3 fatty acids (called DHA and EPA) that have been closely linked to cardiovascular benefit. Note that supplements, when properly purified, avoid the problem of mercury contamination, a concern for those who eat sea food regularly.

Niacin, a B vitamin, is still one of the best agents for supporting cardiovascular health. In a long-term study, it was associated with lower risk of cardiovascular disease and death related to cardiovascular disease. (Don’t be misled by some recent reports about Niacin’s lack of effect, which only appeared in a study using a particular form of the supplement together with a statin drug.) The main drawback of Niacin is that it may cause flushing and itching, which make it difficult or impossible for some to take. Starting with a low dose of about 100 mg and working up to about 1,000 mg per day may minimize this reaction.

Other helpful agents include carnitine (which may lower triglycerides), pantethine (a B vitamin) and phytosterols, such as those in Douglas Labs’ CardioEdge.

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Care for your Heart

CATIE has an excellent review of heart health, abstract below. It reviews the risk factors, methods for assessing heart health and means to help reduce risk of heart attack and stroke. There is a special emphasis on issues affecting people living with HIV.

Fact Sheets

HIV and cardiovascular disease: keeping your heart and blood vessels healthy
Summary

Cardiovascular disease affects the health of your heart and blood vessels and can lead to heart attacks or stroke. You may think that these are problems that affect only older people. However, emerging research suggests that HIV infection increases the risk for cardiovascular disease, including heart attacks and stroke, even in relatively young people. So, regular monitoring by your doctor of your overall and cardiovascular health should be part of your plan for living longer and living well. Getting on treatment for HIV is one of the best things you can do to stay healthy. This Fact Sheet has many additional steps you can take to reduce your risk for heart attacks, stroke and other complications.

This CATIE fact sheet addresses the potential of certain supplements to support cardiovascular health: Omega-3 fatty acids (fish oil); niacin; carnitine; CoQ10; and chromium (subject of an interesting small study in Canada).

Read more about supplements for cardiovascular health at NYBC’s pages on “Cholesterol/Triglycerides” at
http://nybcsecure.org/index.php?cPath=35 and on “CoQ10” at http://nybcsecure.org/index.php?cPath=47 (includes practical suggestions for optimizing your use of CoQ10).

NEW! Managing and Preventing HIV Med Side-Effects

To mark its fifth anniversary, the New York Buyers’ Club has prepared a special edition of SUPPLEMENT. In it you will find a concise Guide to managing and preventing HIV medication side effects with supplements and other complementary and alternative therapies.

This is an invaluable introduction to how nutritional supplements can be used to counter those side effects that can make life miserable–or even disrupt treatment adherence–in people taking antiretroviral medications for HIV.

Read about approaches to dealing with diarrhea, nausea, heart health issues, diabetes, insomnia, fatigue, liver stress, lipodystrophy, anxiety and depression.

This FREE Guide is available online at:

http://newyorkbuyersclub.org/

On the NYBC website you can also SUBSCRIBE to the nonprofit co-op’s quarterly FREE newsletter, THE SUPPLEMENT, which continues to offer a unique perspective on current evidence-based use of supplements for chronic conditions including cardiovascular disease, diabetes/insulin resistance, hepatitis and other liver conditions, anxiety/depression, osteoarthritis, cognitive and neurorological issues, and gastrointestinal dysfunction.

Pantethine for cholesterol control

Pantethine, a biologically active form of pantothenic acid or Vitamin B5, has been used for several decades in Japan and Europe to treat fatty liver and as an adjunct treatment in managing cholesterol. In the US, pantethine is available as a dietary supplement. Research points to its ability to lower LDL (the so-called “bad” cholesterol) and triglycerides, while raising HDL (the so-called “good” cholesterol). A good review of pantethine may be found on the website of the Oregon State University/Linus Pauling Institute:

http://lpi.oregonstate.edu/infocenter/vitamins/pa/

For people with HIV who are using nutritional supplements to help improve their lipid profile, there’s a good info sheet from the Canadian AIDS Treatment Information Exchange, featuring a description of pantethine:

http://www.catie.ca/pdf/Supple-e/Nutrients_e.pdf

See also the NYBC entry on Pantethine for a description of its role in lipid metabolism.