Pomegranate juice and heart health

In the past decade, there have been a number of studies of the potential of pomegranate juice to support cardiovascular health and provide additional health benefits as well. Recently we reviewed a research report published in 2012 that looked at the cardiovascular and immune system benefits of pomegranate juice for hemodialysis patients. This was a randomized placebo controlled double-blind trial (a kind of research design that is likely to produce reliably objective findings). The patients were followed for one year as they used pomegranate juicee three times a week while continuing their dialysis treatments. The results:

Pomegranate juice intake resulted in a significantly lower incidence rate of the second hospitalization due to infections. Furthermore, 25% of the patients in the pomegranate juice group had improvement and only 5% progression in the atherosclerotic process, while more than 50% of patients in the placebo group showed progression and none showed any improvement.

And the conclusion:

Prolonged pomegranate juice intake improves nontraditional CV [cardiovascular] risk factors, attenuates the progression of the atherosclerotic process, strengthens the innate immunity, and thus reduces morbidity among HD [hemodialysis] patients.

Of course, this research involved a special group of patients, those on hemodialysis. But, as a well-designed study, it does, we think, provide a fairly strong endorsement of the health benefits of pomegranate juice.

For more on pomegranate juice, see the NYBC entry

http://nybcsecure.org/product_info.php?cPath=40&products_id=333

Note that NYBC also carries the Douglas supplement Cardio-Edge, which includes pomegranate:

http://nybcsecure.org/product_info.php?cPath=35&products_id=284

Reference: Shema-Didi, L et al. One year of pomegranate juice intake decreases oxidative stress, inflammation, and incidence of infections in hemodialysis patients: a randomized placebo-controlled trial. Free Radic Biol Med. 2012 Jul 15;53(2):297-304. doi: 10.1016/j.freeradbiomed.2012.05.013. Epub 2012 May 17.

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Pomegranate Juice

Pomegranate juice has become a very popular new drink among the health-conscious in the last few years. Indeed there is an interesting body of research about this fruit, including indications that it may help lower “bad [LDL] cholesterol,” or that it may slow progression of prostate cancer. One caution, however: pomegranate juice may interact with certain drugs, in particular blood pressure-lowering drugs. For that reason, it’s advisable for anyone taking prescription drugs to consult with their health care provider before adding pomegranate juice to their daily routine.

NYBC stocks a pomegranate juice concentrate, which can be mixed with other beverages. Using a concentrate such as this can be significantly less costly than buying the well-known juice brands from your local grocery or health food store.

Here’s the basic NYBC entry:

Pomegranate Juice CONCENTRATE (Jarrow) Each bottle, 12 oz (355 ml) of 100% pomegranate juice concentrate. This is one of the most powerful sources of antioxidants, superior even to blueberries and strawberries. Derived from a California variety, this juice is concentrated to a level of 4 times that of ordinary pomegranate juice…it is thick! The antioxidants found in the juice include ellagic and gallic acid, anthocyanins and tannins, and punicalagin. Punicalagin is perhaps the most powerful. Various studies suggest that this may help to improve the level of glutathione in cells (see the entries on NAC and glutathione), particularly macrophages. It may have benefit for maintaining platelet levels, lowering LDL and sustaining vascular tone.

You can read more in the full entry:

Pomegranate Juice Concentrate (Jarrow)