Effectiveness of Saccharomyces boulardii (a probiotic) for antibiotic-associated diarrhea and for C. difficile infection

A good recent review of the effectiveness of probiotics highlights especially the value of Saccharomyces boulardii for diarrhea associated with antibiotic treatments, and for C. difficile infections (a common, and often quite stubborn, gastrointestinal infection). This review, published in 2009, pools data from a number of studies to draw its conclusions. The author first focuses on antibiotic-associated diarrhea, which is a common side effect of many currently used antibiotics, occurring in up to a third of patients being treated. In the second place, the review looks at C. difficile infection and the clinical evidence for the effectiveness of probiotic treatments. In the case of both antibiotic-associated and C. difficile-associated diarrhea, the author concludes that Saccharomyces boulardii has shown effectiveness as a treatment. Among the other findings of this article: probiotic treatments have a very good safety profile and therefore can be recommended widely; and it is very important to treat using probiotics with documented high quality/potency standards in order to insure beneficial outcomes.

Read more about dosage and uses of Saccharomyces boulardii in the NYBC catalog, which now includes two different choices, both from high-quality producers:

Saccharomyces boulardii – Jarrow

and

Florastor – Biocodex

Reference:

McFarland, L. V. Evidence-based review of probiotics for antibiotic-associated diarrhea and Clostridium difficile infections. Anaerobe/Clinical microbiology 15 (2009) 274–280.
Accessed at http://www.idpublications.com/journals/PDFs/ANAE/ANAE_MostDown_1.pdf

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