Clinical studies have shown repeatedly that CoQ10 has potent abilities to assist the heart muscle, and as an adjunct treatment for angina, congestive heart failure, arrhythmia, hypertension (high blood pressure), and drug toxicity. In Japan, it has been widely used, and over several decades, for these types of heart health issues, and that’s one reason why its potential effectiveness and safety profile are at this point quite well characterized.
Research has also shown that as cellular levels of CoQ10 decrease, HIV disease progresses. Other studies have documented CoQ10’s immune restorative qualities, including restoration of T cell function. Many people with HIV find that CoQ10 is an important nutrient to aid in detoxification if one uses nucleoside analogs (AZT ddI, ddC, d4T, etc.), or other toxic drugs. (For example, studies have shown clear benefit when used with a heart toxic chemotherapy drug called adriamycin.)
In addition, we’ve seen widely circulated the recommendation, based on various levels of evidence, that people taking statin drugs—used to manage cholesterol—also take CoQ10. (Levels of CoQ10 in the blood are notably depleted when using this class of drugs, and there is potential for metabolic disruptions in the body as a result.)
A 2007 pilot study showed relief of muscle pain (myopathy) in people taking statins who also took 100mg/day of CoQ10. However, we have also found recommendations for higher dosages (200mg/day or more) for a variety of heart-related conditions.
For further details, see NYBC’s entry on Q-sorb Plus 100mg (Jarrow), specifically designed for enhanced absorption.
See also other forms of CoQ10, at both higher and lower dosages and in combination with other supplements, at