Here is an excerpt from Dr. Hyla Cass’s recommendations for use of alpha lipoic acid for diabetes (as found in her excellent guide, Supplement Your Prescription: What Your Doctor Doesn’t Know About Nutrition, pp 54-55):
“Diabetics require strong antioxidant protection, and alpha-lipoic acid fits this bill. This ‘super antioxidant’ has been found to have healing effects on neuropathy in diabetics, as well as to control insulin resistance. […] ALA has been found to help insulin work better, and to promote production of glutathione, a powerful antioxidant made in the liver. Its use even in medication-dependent diabetics has been shown to reduce complications.”
Caution: Diabetics should inform their doctor if taking alpha lipoic acid, because it can reduce blood sugar levels and can consequently lower need for insulin or other diabetes medications.
Suggested dosage: 200-600mg/day
See also the NYBC entry on Alpha Lipoic Acid.