08.31.09

Pomegranate Juice

Posted in cardiovascular health, pomegranate tagged , , , , , at 3:48 pm by jarebe

Pomegranate juice has become a very popular new drink among the health-conscious in the last few years. Indeed there is an interesting body of research about this fruit, including indications that it may help lower “bad [LDL] cholesterol,” or that it may slow progression of prostate cancer. One caution, however: pomegranate juice may interact with certain drugs, in particular blood pressure-lowering drugs. For that reason, it’s advisable for anyone taking prescription drugs to consult with their health care provider before adding pomegranate juice to their daily routine.

NYBC stocks a pomegranate juice concentrate, which can be mixed with other beverages. Using a concentrate such as this can be significantly less costly than buying the well-known juice brands from your local grocery or health food store.

Here’s the basic NYBC entry:

Pomegranate Juice CONCENTRATE (Jarrow) Each bottle, 12 oz (355 ml) of 100% pomegranate juice concentrate. This is one of the most powerful sources of antioxidants, superior even to blueberries and strawberries. Derived from a California variety, this juice is concentrated to a level of 4 times that of ordinary pomegranate juice…it is thick! The antioxidants found in the juice include ellagic and gallic acid, anthocyanins and tannins, and punicalagin. Punicalagin is perhaps the most powerful. Various studies suggest that this may help to improve the level of glutathione in cells (see the entries on NAC and glutathione), particularly macrophages. It may have benefit for maintaining platelet levels, lowering LDL and sustaining vascular tone.

You can read more in the full entry:

Pomegranate Juice Concentrate (Jarrow)

08.28.09

Red wine, resveratrol and cancer prevention

Posted in cancer, resveratrol tagged , , at 4:56 pm by jarebe

Research on resveratrol, a compound found in red wine, continues to draw media attention, especially as biotech companies in recent years have poured millions into potential patentable compounds that could have dramatic “anti-aging” properties. One of the most interesting health effects of resveratrol is its anti-cancer power, and so we recently decided to stop in at the National Cancer Institute/National Institutes of Health general information page on red wine, resveratrol and cancer prevention, just to see how this particular aspect is being presented. This federal government site aims to keep up with reseach trends in cancer prevention (though actually this particular fact sheet seems a bit behind the curve), and usually provides a quite cautious viewpoint on the evolving research. Here’s a short extract:

The cell and animal studies of red wine have examined effects in several cancers, including leukemia, skin, breast, and prostate cancers. Scientists are studying resveratrol to learn more about its cancer preventive activities. Recent evidence from animal studies suggests this anti-inflammatory compound may be an effective chemopreventive agent in three stages of the cancer process: initiation, promotion, and progression.

Research studies published in the International Journal of Cancer show that drinking a glass of red wine a day may cut a man’s risk of prostate cancer in half and that the protective effect appears to be strongest against the most aggressive forms of the disease. It was also seen that men who consumed four or more 4-ounce glasses of red wine per week have a 60 percent lower incidence of the more aggressive types of prostate cancer.

However, studies of the association between red wine consumption and cancer in humans are in their initial stages. Although consumption of large amounts of alcoholic beverages may increase the risk of some cancers, there is growing evidence that the health benefits of red wine are related to its nonalcoholic components.

You can read more at

http://www.cancer.gov/cancertopics/factsheet/prevention/redwine

08.20.09

SUPPLEMENTS AND OTHER SMART STRATEGIES FOR LONGER LIVING – A panel discussion on traditional, complementary and alternative treatments for HIV

Posted in Carnitine, Coenzyme Q10, Nepal, THE SUPPLEMENT - Newsletter of NYBC, Traditional Chinese Medicine, alpha lipoic acid, cardiovascular health, diarrhea, fatigue, hiv, insulin resistance, lipodystrophy, neuropathy tagged , , , , at 10:54 am by jarebe

We reprint below our report on this June 2009 forum, which brought together a range of views on managing HIV:

SUPPLEMENTS AND OTHER SMART STRATEGIES FOR LONGER LIVING was the title of a panel discussion on traditional, complementary and alternative therapies for HIV presented on June 25, 2009 by the New York Buyers’ Club in celebration of its fifth anniversary. The event brought together experts whose knowledge spans East and West, and whose experience ranges from community organizing and scientific writing, to clinical research and the practice of medicine, whether as an M.D. or as a licensed acupuncturist and specialist in Chinese herbalism.

NYBC was especially proud to host our Guest of Honor, Sunil Pant, the first openly gay Member of Parliament in Nepal, and Founder/Director of the HIV-support organization the Blue Diamond Society, which was recognized by the International Gay and Lesbian Human Rights Commission in 2007 as “one of the most effective human rights groups in the world.” At the start of the panel discussion, our Guest of Honor gave a moving account of the work he and his organization have done over the last decade in securing rights for sexual minorities in Nepal, and in fighting for decent treatment of Nepalis with HIV/AIDS. Sunil also took a moment to recall the many years he has known and worked with our own George Carter, who has directed NYBC efforts to provide supplements and other aid to BDS.

We also felt privileged to hear from our other panelists: Dr. Paul Bellman, a NYC physician who has been treating people with HIV/AIDS since the start of the epidemic; Tim Horn, President and Editor of AIDSmeds.com; Alex Brameier, a licensed acupuncturist and herbalist; and George Carter, Director of the Foundation for Integrative AIDS Research. It’s true that the first two of these panelists are in the mainstream of AIDS treatment practice, by which we only mean to say that their main area of expertise is antiretroviral pharmaceuticals. Yet Dr. Bellman also spoke of the usefulness of several supplements that NYBC and its predecessor DAAIR have long recommended: alpha lipoic acid, carnitine, and CoQ10. Tim Horn, whose website focuses largely on pharmaceutical treatments, nevertheless also acknowledged that the “holistic” approach to long-term health for people with HIV makes a lot of sense. And he went on to say that he recognizes that a whole range of “therapies” (including even diet and exercise) may be needed to address worrisome trends in heart and lung disease among people with HIV who are taking ARVs.

Alex Brameier, the Lic. Ac. on our panel, engaged our audience with an impromptu survey on how people view their acupuncture treatments. She then discussed some of the conditions that lend themselves to acupuncture, based on clinical experience: pain relief, stress reduction, neurological and musculoskeletal disorders, to name a few. Very useful as well was the contrast she drew between acupuncture as practiced in China and Japan (where treatment may be daily or every other day), and the West, where time and financial constraints often dictate otherwise. Her tips on how to get the best out of acupuncture and how acupuncture and herbs can work together were also very valuable.

Last but not least among our contributors was George Carter, who’s had two decades of experience with supplements, from clinical research to acting as NYBC Treatment Director. George, as all who know him can attest, is nothing if not thorough, and for this event he prepared a “Short Primer on Side Effects,” a compact but comprehensive review of HIV medication side effects, ranging from malabsorption/diarrhea//nausea, to lipid abnormalities (of concern for cardiovascular health), to fatigue and insomnia, to insulin resistance/diabetes, to liver damage, to bone issues, to peripheral neuropathy. We hope to produce this super-useful handout as a handy pocket guide in the near future, so stay tuned.

An inspirational, lively, and (if we do say so ourselves) immensely informative event. If you were there, thanks for coming! And if not–we certainly hope to see you at the next one.

Reprinted from the SUMMER 2009 SUPPLEMENT: Newsletter of the New York Buyers’ Club, which can be read in its entirety at

http://newyorkbuyersclub.org/supplement/index.html

In addition to the piece above, this issue contains a report on how research on diet and nutrition has led to new knowledge about supplements (“Are You Ready to Join the Food Revolution?”), and a short review on HIV and cognitive impairment.

Note: Email subscriptions to THE SUPPLEMENT are free to NYBC members.

08.12.09

B vitamins and brain function: the latest studies

Posted in Alzheimer's Disease, B vitamins, Vitamin B12 tagged , , , , , , at 1:22 pm by jarebe

The evidence continues to pile up that levels of the B vitamins, in particular B6 (pyridoxine), B9 (folate), and B12 (cyanocobalamin), are closely related to maintaining cognitive function and warding off brain-related disorders like Alzheimer’s as we age. Well-designed studies, including the Veterans Affairs (VA) Normative Aging Study, have pointed particularly to Vitamin B deficits being associated with buildup of homocysteine, which in turn may be responsible for impairment to cognitive function.

B Vitamins are central to the preservation of mental capacities as we age. At the same time, the aging digestive system may not absorb nutrients as effectively as it once did; so an obvious strategy is to consider B complex supplementation as well as good dietary habits as we get older.

Read more on the B vitamins on the NYBC site:

B-right (Jarrow) We selected this as a good comprehensive B vitamin supplement.

B-12 Methylcobalamin (Jarrow) Studies have suggested that this is a very effective way to supplement with B12, which may not always be well-absorbed by the body when taken in other formats.

Some References:

Kim JM, Stewart R, Kim SW Changes in folate, vitamin B12 and homocysteine associated with incident dementia. J Neurol. Neurosurg. Psychiatry 2008;79;864-868.

Tucker KL, Qiao N, Scott T, et al. High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study. Am J Clin Nutr. 2005 Sep;82(3):627-35.

Wang HX, Wahlin A, Basun H, et al. Vitamin B12 and folate in relation to the development of Alzheimer’s disease. Neurology 2001;56:1188-94.

08.04.09

Millions of American Children Have Low Vitamin D Levels, Putting Them at Risk for Bone Problems, Heart Disease, Diabetes, and other Ailments

Posted in Vitamin D, blood pressure, cardiovascular health, diabetes tagged , , , , , , at 4:36 pm by jarebe

This is the lead in a Washington Post story published Aug. 3, 2009, which summarizes findings from two new studies that provide the first national snapshot of a nutrient whose importance to health has been emphasized by a raft of recent investigations. (Check the entry “Vitamin D” in this blog for some of these other research findings.)

The new studies on Vitamin D come as the National Academy of Sciences Institute of Medicine is reviewing official guidelines for daily intake of Vitamin D. Many researchers in recent years have suggested that the recommended daily intake should be increased, particularly to counteract deficiencies detected in certain groups with chronic conditions.

The national studies, which showed millions of American children deficient in Vitamin D, also highlighted worrisome associations between low Vitamin D levels and high blood pressure, high blood sugar, and “metabolic syndrome,” a condition that increases risk of heart disease and diabetes.

One source of Vitamin D is sunlight–the body manufactures the vitamin in response to exposure to the sun. And the recent research suggests that American children, prone to watch TV and play videogames, may not be getting enough outdoor time and sunlight, leading to the Vitamin D deficiency. Others point out that too much exposure to the sun may lead to higher rates of skin cancer, already the leading type of cancer in the US. Of course–we note–supplementing with Vitamin D could address the deficiency, while also avoiding the increased skin cancer risk that comes with exposure to sun.

See the following product entries on the NYBC website for further information on Vitamin D:

D3-1000 (Jarrow)

D3-400 (Jarrow)

Bone-Up (Jarrow) – includes D3 plus other nutrients important for bone health

Bone-Up – Ultra (Jarrow) – additional nutrients compared to the regular “Bone-Up”, plus a larger quantity

08.02.09

Bromelain: a digestive enzyme derived from pineapple

Posted in Bromelain, digestive enzymes, hiv tagged , , , , at 4:11 pm by jarebe

Bromelain, an extract from pineapple fruit and stems, is a “proteolytic enzyme,” meaning that it helps in the digestion of proteins (not fats or sugars).

We were interested to read this recent study reported about Bromelain
used to treat a rash called “pityriasis lichenoides chronica,” which has been associated with HIV and Epstein-Barr:

Massimiliano R, Pietro R, Paolo S, Sara P, Michele F. Role of bromelain in the treatment of patients with pityriasis lichenoides chronica. J Dermatolog Treat. 2007;18(4):219-22.

OBJECTIVES: Pityriasis lichenoides chronica (PLC) is a skin disease of unknown etiology. Uncertainty about the etiopathogenesis of this skin disease is the reason for the unpredictable and non optimal efficacy of therapies available for its treatment. The aim of the present study was to evaluate the efficacy of bromelain, a crude aqueous extract of the stems and immature fruit of pineapple, in the treatment of PLC. MATERIALS AND METHODS: Eight patients (3 males and 5 females) with PLC were enrolled in the study and treated for three months with oral bromelain (40 mg 3 times a day for 1 month, 40 mg twice a day for 1 month and 40 mg/day for 1 month). RESULTS: All patients showed complete clinical recovery after treatment. In 12 months of follow up, two patients experienced relapse 5-6 months after suspension of therapy but responded to another brief cycle of therapy. No side effects were encountered during therapy. CONCLUSIONS: In conclusion bromelain can be considered an effective therapeutic option for PLC; its efficacy could be related to its anti-inflammatory, immunomodulatory and/or anti-viral properties.

See also the NYBC entry:

Bromelain

Low vitamin D common among HIV+ people

Posted in Vitamin D, hiv tagged , , at 2:47 pm by jarebe

Poz magazine reports on a study revealing a high degree of vitamin D deficiency among people with HIV. The data are piling up on the significance of this inexpensive vitamin. Vitamin D deficiency is particularly widespread among African Americans.

See http://www.poz.com/rssredir/articles/hiv_vitamind_bone_761_17003.shtml